Peer-reviewed veterinary case report
Ivermectin stops Strongyloides larvae in naturally infected dogs
By Mansfield, L S & Schad, G A·Published in Journal of the American Veterinary Medical Association·1992·Department of Pathobiology, United States·View original on PubMed →
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Original publication title: Ivermectin treatment of naturally acquired and experimentally induced Strongyloides stercoralis infections in dogs.
- Species:
- dog
Plain-English summary
Two dogs with a chronic infection caused by a parasite called Strongyloides stercoralis were treated with a single dose of ivermectin. After treatment, both dogs stopped shedding the parasite in their feces within a week, although one dog needed a second dose due to a return of the infection. In a separate group of three dogs with a more severe form of the infection, ivermectin completely cleared the adult parasites from their intestines, but it did not eliminate all larvae from other sites in the body. Overall, ivermectin proved to be effective in treating these infections in dogs.
People also search for: dog parasite treatment · ivermectin for Strongyloides in dogs · dog feces parasite infection
Abstract
Treatment of Strongyloides stercoralis infection was investigated in 2 dogs with naturally acquired, chronic-active infections, and in 3 dogs with corticosteroid-enhanced, experimentally induced hyperinfections. A single oral dose of ivermectin was given to naturally infected (200 micrograms/kg of body weight) and experimentally infected (800 micrograms/kg) dogs. Five dogs with experimental hyperinfections served as controls. Dogs with naturally acquired infections ceased to shed first-stage larvae in the feces 1 week after treatment, but 1 dog had recrudescence and required a second dose. Ivermectin was 100% effective in removing adult S stercoralis from the intestinal tract of the experimentally infected dogs, but it was not effective in removing third-stage larvae from parenteral sites. Ivermectin-treated dogs had few intestinal parasites of any stage, whereas at necropsy, 4 of 5 experimentally infected dogs not treated had massive infections (greater than 100,000 adults, greater than 92,000 larvae) in the intestinal tract, and 3 of 5 had larvae (greater than 2,500) in parenteral sites.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1399774/