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Peer-reviewed veterinary case report

Junctional epidermolysis bullosa in two domestic shorthair kittens.

Journal:
Veterinary dermatology
Year:
2005
Authors:
Alhaidari, Zeineb et al.
Affiliation:
Clinique V&#xe9 · France
Species:
cat

Abstract

This article describes two cases of junctional epidermolysis bullosa in nonrelated kittens. Both cats exhibited pinnal erosions, oral ulcerations and severe onychomadesis. Histopathology, electron microscopy and/or indirect immunoperoxidase revealed subepidermal clefting, with the lamina densa remaining attached to the floor of the vesicles. Indirect immunofluorescence revealed reduced staining for laminin-5 gamma2 subunit in case 1 and beta3 subunit in case 2.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15725108/