Peer-reviewed veterinary case report
Klossiella equi induced tubular nephrosis and interstitial nephritis in a pony.
- Journal:
- Journal of comparative pathology
- Year:
- 1988
- Authors:
- Anderson, W I et al.
- Affiliation:
- Department of Veterinary Pathology · United States
Plain-English summary
A pony was found to have a serious kidney infection caused by a parasite called Klosiella equi. This infection led to damage in the kidney's tiny tubes and some of them even ruptured. The pony also had inflammation in the kidney tissue, which was linked to the ruptured tubes. It seems that the pony's body was producing too many stress hormones, which weakened its immune system and allowed the parasite to multiply rapidly. The outcome of this situation is not specified, so it’s unclear how the pony responded to treatment.
Abstract
Heavy renal infection in a pony with Klosiella equi resulted in moderate diffuse tubular nephrosis and tubular rupture. Multifocal non-suppurative interstitial nephritis was associated with ruptured tubules. Ultrastructural examination of sporoblasts demonstrated both the presence of a bilaminated membrane encasing organisms and nuclear budding. Endogenous corticosteroid production probably led to the development of an immune-compromized state and subsequent extensive parasitic replication.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/3392250/