Peer-reviewed veterinary case report
l-Serine Lowers the Inflammatory Responses during Pasteurella multocida Infection.
- Journal:
- Infection and immunity
- Year:
- 2019
- Authors:
- He, Fang et al.
- Affiliation:
- College of Animal Science and Technology · China
Abstract
causes a variety of infectious diseases in various species of mammals and birds, resulting in enormous economic loss to the modern livestock and poultry industry. However, the mechanism of host-pathogen interaction is unclear. Here, we found that l-serine levels were significantly decreased in murine lungs infected withExogenous l-serine supplementation significantly increased the survival rate of mice and decreased the colonization ofin the lungs of mice. Notably, l-serine decreased the macrophage- and neutrophil-mediated inflammatory responses in mice duringinfection.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31570555/