Labial calcinosis circumscripta in a dog with history of Hymenopteran stings in oral cavity - case report

Abstract

ABSTRACT Calcinosis circumscripta (CC) is a benign lesion characterized by focal-to-multifocal mineralized deposits mainly in the cutaneous and subcutaneous tissues. CC is uncommon in the oral cavity of dogs and its etiopathogenesis is unclear. Its differential diagnosis includes non-proliferative to neoplastic lesions that course with leukoplakia in the oral mucosa. This study describes the case of a 2-year-old male Shih-Tzu dog, who presented with increased volume on the inner surface of the lower lip and a history of Hymenoptera (bee and wasp) stings at the site of the injury. The lesion was diagnosed via excisional biopsy based on the gross and microscopic characteristics. In addition to contributing to the differential diagnosis of lesions with leukoplakia in the oral mucosa of dogs, to the best of our knowledge, this is the first report of labial CC in a dog with history of Hymenopteran stings suggesting a potential complication of Hymenopteran venom-induced lesions in the oral cavity of dogs.