Peer-reviewed veterinary case report
How lab tests diagnose urine in dog belly fluid
By Paes, Paulo R O et al.·Published in Veterinary clinical pathology·2022·Department of Veterinary Clinic and Surgery, Brazil·View original on PubMed →
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Original publication title: Laboratory diagnosis of canine uroperitoneum based on cellular and biochemical characteristics of serum and abdominal fluid.
- Species:
- dog
Plain-English summary
A study looked at 180 dogs with fluid in their abdomen, including 30 cases of uroperitoneum, which is when urine leaks into the abdominal cavity. The researchers found that using specific tests for fluid creatinine levels and ratios could accurately diagnose uroperitoneum in dogs. They discovered that 83.3% of the uroperitoneum cases had fluid that didn't fit typical classifications, but by applying new criteria, they achieved a 99% accuracy rate in identifying this condition. This means that vets can now better diagnose and treat dogs with this serious issue.
People also search for: dog abdominal fluid diagnosis · uroperitoneum in dogs · dog urine leak treatment
Abstract
BACKGROUND: Literature on the laboratory diagnosis of uroperitoneum is scarce, and it is mostly based on the biochemical findings of cavitary fluid and serum. Cell count and protein concentrations measurements are rarely used and available studies on this subject are based on a relatively small cohort of individuals. OBJECTIVES: We aimed to use a large sample pool of dogs to establish cutoff points for biochemical analytes in cavitary fluids and serum for the diagnosis of uroperitoneum. We also sought to evaluate the general classification of these cavitary fluids. METHODS: In a retrospective and prospective study, 180 canine abdominal effusion cases were evaluated, 30 of which were uroperitoneum (uroperitoneum group, UG) and 150 with other etiologies (non-uroperitoneum group, NUG). RESULTS: The results showed that 83.3% of UG and 12.7% of NUG abdominal fluid cases were not classified as transudates or exudates. The use of specific cutoffs for fluid creatinine concentrations (≥2.1 mg/dL) and fluid:serum creatinine ratios (Cf: Cs ≥ 1.25) in these unclassified effusions resulted in an accuracy of 99.0% for the laboratory diagnosis of uroperitoneum. CONCLUSIONS: The adoption of a new set of criteria and cutoffs based on the combination of parameters such as TP, TNCC, fluid creatinine and Cf: Cs improves the diagnosis of uroperitoneum in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35181924/