Peer-reviewed veterinary case report
Lack of association between the occurrence of Crohn's disease and occupational exposure to dairy and beef cattle herds infected with Mycobacterium avium subspecies paratuberculosis.
- Journal:
- Journal of dairy science
- Year:
- 2010
- Authors:
- Qual, D A et al.
- Affiliation:
- Department of Veterinary Microbiology and Preventive Medicine · United States
Plain-English summary
Researchers looked into whether there is a link between Crohn's disease (a type of inflammatory bowel disease) and exposure to cattle infected with a specific bacteria called Mycobacterium avium subspecies paratuberculosis (Map). They surveyed dairy and beef cattle producers, as well as veterinarians, asking about their contact with infected herds and any personal or family history of Crohn's disease. Out of over 1,400 participants, only a few cases of Crohn's disease were found, and the study did not find any connection between being around infected cattle and developing the disease. However, the small number of cases means that the study might not have been able to detect any real differences. Overall, the findings suggest that there is no strong evidence linking Map exposure to Crohn's disease.
Abstract
A cross-sectional survey was conducted to identify associations between Crohn's disease (CD) and Mycobacterium avium ssp. paratuberculosis (Map) exposure. A questionnaire was used to collect information on exposure to cattle infected with Map, and personal and family history of CD in dairy and beef cattle producers with and without Map-infected herds, and in veterinarians who did or did not have contact with Map-infected herds. Cases of CD were selected from respondents and matched 1:4 with controls on occupation, age, and sex. Multivariable conditional logistic regression was used to assess associations between Map exposure and CD. There were 3 cases of CD in 702 producers and 4 cases in 774 veterinarians, yielding a prevalence of 0.47%. No association was found between exposure to JD and CD in any phase of the analysis. However, the number of cases of CD is not large and limits the power to detect important differences.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20494145/