Peer-reviewed veterinary case report
Lack of protection against ebola virus from chloroquine in mice and hamsters.
- Journal:
- Emerging infectious diseases
- Year:
- 2015
- Authors:
- Falzarano, Darryl et al.
- Species:
- rodent
Abstract
The antimalarial drug chloroquine has been suggested as a treatment for Ebola virus infection. Chloroquine inhibited virus replication in vitro, but only at cytotoxic concentrations. In mouse and hamster models, treatment did not improve survival. Chloroquine is not a promising treatment for Ebola. Efforts should be directed toward other drug classes.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25988934/