Peer-reviewed veterinary case report
Langerhans cell histiocytosis of the maxillae in a child treated only with chemotherapy: a case report
- Journal:
- Journal of Medical Case Reports
- Year:
- 2017
- Authors:
- Angela Pia Cazzolla et al.
- Affiliation:
- Department of Translational Medicine, University of Bari · GB
- Species:
- dog
Abstract
Abstract Background Langerhans cell histiocytosis is a sporadic disease caused by an uncontrolled pathogenic clonal proliferation of dendritic cells that have Langerhans cell characteristics. New treatment protocols provided by the HISTSOC-LCH-III (NCT00276757) trial show an improvement in the survival of children with langerhans cell histiocytosis. Case presentation We report a case of Langerhans cell histiocytosis, which presented as an osteolytic lesion of the left pre-maxillae enclosing the deciduous incisor and canine in a 7-month-old white Italian boy. He was treated with chemotherapy. He achieved complete remission after 7 months and after 24 months no signs of recurrence were observed. Conclusions As a result of this treatment, anesthetic sequelae and loss of teeth were avoided; in addition, we prevented a loss of the vertical dimension of occlusion.
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Search related cases →Original publication: https://doi.org/10.1186/s13256-017-1286-3