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Peer-reviewed veterinary case report

Laser-welded endoscopic endoluminal repair of iatrogenic esophageal perforation: an animal model.

Journal:
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Year:
2008
Authors:
Bleier, Benjamin S et al.
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery · United States
Species:
rabbit

Abstract

OBJECTIVE: To test the feasibility of laser tissue welding (LTW) in creating an endoscopic transluminal repair of esophageal perforation. STUDY DESIGN: Animal model. SUBJECTS AND METHODS: A diode laser was used to create an endoluminal rabbit esophageal perforation repair. Burst pressures were compared with open incision, external suture, and external laser-augmented suture closure. Comparisons were performed five times and analyzed with Kruskal-Wallis analysis of variance and a post hoc Dunn method. RESULTS: The burst threshold of the endoluminal weld (54.78 +/- 5.84 mm Hg) was significantly higher than that of the open incision (6.5 +/- 1.94 mm Hg) and not significantly different than that of the external suture (37.18 +/- 1.97 mm Hg) or the laser-augmented suture group (71.60 +/- 7.58 mm Hg). CONCLUSION: Laser welding is a feasible method of creating endoluminal repairs with burst strengths comparable with external suture repair, which may allow a subset of patients to avoid traditional open approaches. This is the first reported animal model of LTW for endoscopic closure of iatrogenic esophageal perforation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18984269/