Peer-reviewed veterinary case report
Blindness and brain white matter damage in young Labrador puppies
By Neer, T M & Kornegay, J N·Published in Journal of veterinary internal medicine·1995·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Leucoencephalomalacia and cerebral white matter vacuolar degeneration in two related Labrador retriever puppies.
- Species:
- dog
Plain-English summary
Two related Labrador Retriever puppies, both 5 months old, were brought in for neurological issues like blindness, dullness, and forgetting learned behaviors. Tests showed they had leucoencephalomalacia (a type of brain damage) and vacuolar degeneration in their brain's white matter. Interestingly, a full sibling of one of the puppies showed similar symptoms at 1.5 years old, but those symptoms did not worsen over the next two years. Unfortunately, there is no specific treatment mentioned for these conditions, and the long-term outlook for the puppies remains uncertain.
People also search for: Labrador puppy blindness · neurological problems in puppies · leucoencephalomalacia in dogs
Abstract
Two Labrador Retriever dogs from a common dam had similar neurological deficits consisting of cortical blindness, dullness, and loss of previously learned habits. Both were examined at 5 months of age, and histopathological examination revealed leucoencephalomalacia and vacuolar degeneration of the cerebral white matter. Histopathologic findings in these 2 dogs differed from those reported previously in Labrador Retrievers with spongy degeneration of central nervous system white matter. A nonlittermate full sibling to 1 of these dogs was examined at 1.5 years of age for similar clinical signs that did not progress for the next 25 months.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7760308/