Peer-reviewed veterinary case report
Weimaraner dog with brain inflammation and blood vessel damage
By Berrocal, A et al.·Published in Veterinary pathology·2000·Escuela de Medicina Veterinaria·View original on PubMed →
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Original publication title: Leukoencephalitis and vasculitis with perivascular demyelination in a Weimaraner dog.
- Species:
- dog
Plain-English summary
A 7-year-old Weimaraner was experiencing multiple episodes of neurological issues, which ultimately led to the decision to euthanize the dog. A postmortem examination revealed serious damage in the brain and spinal cord, including inflammation and injury to the white matter. The findings suggested a type of immune response that caused blood vessel inflammation and damage to the protective covering of nerve fibers. Unfortunately, the dog did not recover, and the condition was linked to an immune-related disorder affecting the central nervous system.
People also search for: Weimaraner neurological problems · dog brain disease symptoms · immune system issues in dogs
Abstract
Aseptic and noninfectious diseases of the central nervous system are being recognized with increasing frequency. After multiple episodes of neurologic illness, this 7-year-old Weimaraner dog was euthanatized and submitted for postmortem examination. Lesions in the central nervous system were found mainly in the white matter of the cerebral cortex and cervical spinal cord and represented acute and more chronic injury. Necrotizing vasculitis with fibrinoid change and a marked neutrophilic infiltrate dominated the acute lesions. More chronic changes consisted of perivascular demyelination and accumulation of foamy macrophages with positive staining for myelin. An immune-complex (Arthus-type) vasculitis is suspected.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11055872/