Peer-reviewed veterinary case report
House dust mite allergy blood test results in cats
By Bexley, Jennifer et al.·Published in Veterinary dermatology·2009·YorkTest Veterinary Services, United Kingdom·View original on PubMed →
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Original publication title: Levels of house dust mite-specific serum immunoglobulin E (IgE) in different cat populations using a monoclonal based anti-IgE enzyme-linked immunosorbent assay.
- Species:
- cat
Plain-English summary
A group of cats with signs of allergic dermatitis (skin allergies) had their blood tested for a specific type of allergy-related protein (IgE) linked to house dust mites. The study found that cats with allergic dermatitis had higher levels of this IgE compared to nonallergic cats, particularly when exposed to one type of dust mite. In contrast, cats that were kept free of specific pathogens had much lower levels of this IgE. While the findings suggest that one type of dust mite may be a significant trigger for allergies in some cats, more research is needed to fully understand the implications for treatment and management.
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Abstract
Levels of serum immunoglobulin E (IgE) specific for the house dust mites (HDMs) Dermatophagoides farinae (DF) and Dermatophagoides pteronyssinus (DP) in 58 cats with clinical signs suggestive of atopic dermatitis (allergic dermatitis cats), 52 cats with no history of allergic or immunological disease (nonallergic cats) and 26 specific pathogen-free (SPF) cats were measured using a monoclonal anti-IgE enzyme-linked immunosorbent assay. Reactivity to both native and reduced HDM allergens was compared. SPF cats had significantly lower levels of HDM-specific serum IgE than cats with allergic dermatitis and nonallergic cats. The difference in levels of HDM-specific IgE in the serum of cats with allergic dermatitis and nonallergic cats was significant for native DF allergen, but not for native DP allergen or reduced HDM allergens. The results suggest that DF in its native form may be a significant allergen in cats with allergic dermatitis. The clinical relevance of these reactions, however, remains to be proven.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20178495/