Peer-reviewed veterinary case report
Managing ligneous conjunctivitis in a plasminogen-deficient dog over
By Torres, María-Dolores et al.·Published in Veterinary ophthalmology·2009·Departament de Medicina i Cirurgia Animals, Spain·View original on PubMed →
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Original publication title: Ligneous conjunctivitis in a plasminogen-deficient dog: clinical management and 2-year follow-up.
- Species:
- dog
Plain-English summary
A 1-year-old female Yorkshire Terrier was brought to the vet with a 6-month history of persistent eye problems, including swollen masses in her eye and mouth, along with occasional vomiting and coughing. After various treatments failed, the vet diagnosed her with ligneous conjunctivitis, a rare condition linked to low plasminogen levels in her blood. To manage her symptoms, the vet prescribed a combination of heparin eye drops and medications to reduce inflammation and suppress her immune response. Thankfully, this treatment helped control her eye issues, and she was monitored for two years with a good quality of life.
People also search for: dog eye problems treatment · Yorkshire Terrier conjunctivitis · ligneous conjunctivitis in dogs · plasminogen deficiency in dogs
Abstract
A 1-year-old-female Yorkshire Terrier was referred to the Veterinary Teaching Hospital of the Autonomous University of Barcelona (VTH-UAB) (Spain) with a 6-month history of unilateral chronic proliferative conjunctivitis and intermittent vomiting and cough. Several medical and surgical treatment efforts to manage conjunctival lesions had resulted in no improvement of the clinical signs. Complete general and ophthalmic examinations revealed several proliferative 'wood-like' masses in the conjunctiva, oral cavity and an interscapular subcutaneous nodule. Conjunctival and buccal biopsies were performed as diagnostic procedures. A diagnosis of ligneous conjunctivitis was made on the basis of histopathology findings and clinical presentation. The only biochemical abnormalities found were severe proteinuria and low plasminogen activity in plasma. No other analytical abnormalities were observed. Topical treatment with heparin and anti-inflammatory and immunosuppressive drugs have controlled the ophthalmological clinical signs. To our knowledge, this is the first case report of a dog with plasminogen deficiency and ligneous conjunctivitis with a long survival period and 2-year follow-up.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19604341/