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Peer-reviewed veterinary case report

Ligneous conjunctivitis in four Doberman pinschers.

Journal:
Journal of the American Animal Hospital Association
Year:
1996
Authors:
Ramsey, D T et al.
Affiliation:
Department of Small Animal Clinical Sciences · United States
Species:
dog

Abstract

Ligneous conjunctivitis (LC) was diagnosed in four unrelated Doberman pinschers. Thick, opaque membranes of the palpebral conjunctivae and nictitating membranes were present bilaterally. Three dogs had concurrent signs of multisystemic disease. A thick, amorphous, eosinophilic, hyaline-like material in the substantia propria of the conjunctiva--containing a moderate, mononuclear cell infiltrate--was evident on histological examination. A predominance of T lymphocytes, few macrophages, and weak positive staining for immunoglobulin G (IgG) and immunoglobulin A (IgA) were evident by immunohistochemical staining. The clinical and histological appearance of LC in Doberman pinschers and humans is similar.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/8875361/