Peer-reviewed veterinary case report
Limited protection conferred by a DNA vaccine against a lethal pseudorabies virus infection at day 5 postvaccination.
- Journal:
- Clinical and vaccine immunology : CVI
- Year:
- 2007
- Authors:
- Dory, Daniel et al.
- Affiliation:
- Viral Genetics and Biosafety Unit · France
Abstract
No pseudorabies virus (PRV)-specific neutralizing or immunoglobulin G1-type antibodies were detected in sera 5 days after injection of a DNA vaccine against PRV infection in pigs. PRV-stimulated peripheral blood mononuclear cells produced gamma interferon mRNA in vitro. Two out of five pigs recovered from lethal PRV infection without attenuation of nasal viral excretion.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17301217/