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Peer-reviewed veterinary case report

Tongue nerve tumor removed in 9-year-old Chinese Pug dog

By Baratt, Robert M et al.·Published in Journal of veterinary dentistry·2015·View original on PubMed

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Original publication title: Lingual Malignant Peripheral Nerve Sheath Tumor in a Chinese Pug Dog.

Species:
dog

Plain-English summary

A 9-year-old spayed female Chinese Pug was brought in because of a mass on her tongue. After a biopsy, the mass was identified as a malignant peripheral nerve sheath tumor, which is a type of cancer that affects the nerves. The veterinarian performed surgery to remove part of the tongue, ensuring that the tumor was completely excised with healthy tissue around it. Six months after the surgery, the dog was healing well and showed no signs of the tumor returning.

People also search for: dog tongue tumor · Chinese Pug cancer treatment · malignant nerve sheath tumor in dogs

Abstract

A 9-year-old spayed/female Chinese Pug dog presented for evaluation of a mass located on the rostral aspect of the tongue. An incisional biopsy was acquired, submitted, and interpreted as a possible granular cell tumor based on hematoxylin and eosin, and periodic acid Schiff histopathologic staining characteristics. The diagnosis was supported by immunohistochemical evaluation that was positive for S-100, vimentin, and neuron-specific enolase. Based on the absence of mitotic figures in the incisional biopsy, a partial glossectomy was performed with gross margins of at least 1-cm. The excisional biopsy revealed significant features of malignancy, with neoplastic cells in close association with peripheral nerves, consistent with malignant peripheral nerve sheath tumor. Tumor-free margins were obtained, and the glossectomy had expected healing with no recurrence apparent 6-months following surgery.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26638295/