Peer-reviewed veterinary case report
Lipases as modulators of atherosclerosis in murine models.
- Journal:
- Current drug targets
- Year:
- 2007
- Authors:
- Brown, Robert J & Rader, Daniel J
- Affiliation:
- Department of Medicine and Institute for Translational Medicine and Therapeutics · United States
Abstract
Lipoprotein lipase, hepatic lipase, and endothelial lipase are sn-1 lipases that play important roles in the metabolism of plasma lipoproteins. In vitro and in vivo studies suggest that these lipases exhibit both pro- and anti-atherogenic properties, which are dependent primarily on their tissue localization. The following chapter reviews the physiology of these lipases, and the consequences of the loss or gain of function for each lipase in modulating atherosclerosis, with emphasis on murine models.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18220707/