Peer-reviewed veterinary case report
Weakness and muscle pain from lipid storage in a 6-year-old Cocker
By Platt, S R et al.·Published in The Journal of small animal practice·1999·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Lipid storage myopathy in a cocker spaniel.
- Species:
- dog
Plain-English summary
A 6-year-old male cocker spaniel was brought to the vet after showing signs of general weakness and muscle pain for three weeks. Tests, including muscle biopsies, revealed an unusual buildup of fat in his muscle cells, which indicated a problem with how his body was using energy. Although the exact cause of this issue is still unclear, the vet found some changes in his blood and urine that pointed to a metabolic block. Unfortunately, the study does not mention any specific treatments or outcomes for the dog.
People also search for: cocker spaniel weakness · dog muscle pain treatment · lipid storage myopathy in dogs
Abstract
A six-year-old male cocker spaniel was presented to the Veterinary Medical Teaching Hospital, University of Florida, with a three-week history of generalised weakness and myalgia. Electrodiagnostic evaluation, cerebrospinal fluid analysis and thoracolumbar myelography were unremarkable. Biopsies from vastus lateralis and triceps muscles revealed numerous large lipid droplets within type 1 fibres and to a lesser degree within type 2 fibres. The resting plasma lactate was mildly increased and there was elevated urinary excretion of lactic, pyruvic and acetoacetic acids, increased urinary excretion of carnitine esters, and increased plasma alanine. This pattern of metabolite excretion is consistent with an, as yet undefined, block in oxidative metabolism.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10092040/