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Peer-reviewed veterinary case report

Lipid synthesis leads the way for invasive migration.

Year:
2024
Authors:
Machesky LM.
Affiliation:
Department of Biochemistry · United Kingdom

Abstract

Invasive migration requires cells to break through extracellular matrix barriers, which is an energy-expensive process. In this issue, Park et al. (https://doi.org/10.1083/jcb.202402035) highlight the importance of biosynthesis of fatty acids, phospholipids, and isoprenoids in driving invasive migration of the Caenorhabditis elegans anchor cell through a basement membrane barrier during development.

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Original publication: https://europepmc.org/article/MED/39348026