Peer-reviewed veterinary case report
Listeriosis in an Arabian foal with combined immunodeficiency.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1978
- Authors:
- Clark, E G et al.
- Species:
- horse
Plain-English summary
A 1-month-old Arabian foal showed signs of illness affecting its brain and nervous system. Tests revealed that the foal had a combined immunodeficiency, meaning its immune system was not working properly. Despite receiving strong antibiotics, the foal sadly passed away. An examination after death showed serious inflammation in the brain, heart, and adrenal glands, along with other issues. The bacteria Listeria monocytogenes was found in the brain, indicating it was the cause of the illness.
Abstract
A 1-month-old Arabian foal with signs of central nervous system disease was found to have combined (B- and T-lymphocyte) immunodeficiency. The foal died in spite of intensive antibiotic therapy. At necropsy, generalized lymphoid hypoplasia and acute necrotizing and granulomatous inflammation of the brain, heart, and adrenal glands were found. In addition, there were spinal meningitis and focal hepatic necrosis. Listeria monocytogenes was isolated on primary culture from the brain.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/413818/