Peer-reviewed veterinary case report
Little heterogeneity among genes encoding heat-labile and heat-stable toxins of enterotoxigenic Escherichia coli strains isolated from diarrheal pigs.
- Journal:
- Applied and environmental microbiology
- Year:
- 2009
- Authors:
- Zhang, Chengxian et al.
- Affiliation:
- Department of Veterinary Science · United States
Abstract
To examine whether the heat-labile enterotoxin gene in porcine enterotoxigenic Escherichia coli (ETEC) strains is as divergent as in human ETEC strains, we sequenced the heat-labile and heat-stable toxin genes from 52 and 33 porcine ETEC strains, respectively. We found that the STa gene is identical, that the LT gene has only two mutations in 4 (of 52) strains, and that both mutations cause a reduction in GM1 binding and toxicity.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19684170/