Peer-reviewed veterinary case report
Littoral cell angiosarcoma tumor in 12-year-old beagle dog
By Gal, A et al.·Published in Journal of comparative pathology·2013·University of Illinois, United States·View original on PubMed →
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Original publication title: Littoral cell angiosarcoma in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old neutered female Beagle was diagnosed with a mid-splenic mass, which turned out to be a type of cancer called littoral cell angiosarcoma. Unfortunately, despite treatment, the cancer spread, and the dog passed away three months after the diagnosis. The tumor had specific features that indicated it was aggressive, including certain markers that showed it was malignant. This case highlights the seriousness of splenic masses in dogs and the importance of early detection and treatment.
People also search for: dog splenic mass cancer · Beagle cancer symptoms · littoral cell angiosarcoma in dogs
Abstract
This report describes the microscopical and immunohistochemical characteristics of littoral cell angiosarcoma in a 12-year-old, neutered female, beagle dog. The dog succumbed to metastatic disease 3 months after diagnosis of a mid-splenic mass. The tumour was characterized by two histological patterns: anastomosing microvascular channels and microvascular papillary fronds. The neoplastic cells expressed both endothelial and histiocytic markers and were erythrophagocytic. Immunohistochemical findings consistent with malignancy were CD34 expression and high Ki67 nuclear immunoreactivity.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23453493/