Peer-reviewed veterinary case report
Effectiveness and safety of CredelioPlus for dog intestinal worms
By Lee, Subin et al.·Published in Parasitology research·2025·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Local field study on the effectiveness and safety of milbemycin oxime and lotilaner (CredelioPlus) against canine gastrointestinal nematodes in the Republic of Korea.
- Species:
- dog
Plain-English summary
A group of 25 dogs in Korea were treated with a single dose of a combination medication called CredelioPlus to eliminate intestinal worms, including Toxocara canis and Ancylostoma caninum. Fecal tests showed that the treatment was 100% effective in getting rid of these parasites, and the dogs did not experience any side effects or health issues during the study. This suggests that CredelioPlus is a safe and effective option for controlling gastrointestinal worms in dogs.
People also search for: dog intestinal worms treatment · CredelioPlus for dogs · how to treat Toxocara canis in dogs
Abstract
This field study evaluated the effectiveness and safety of a single dose of a combination of milbemycin oxime and lotilaner (CredelioPlus) against Toxocara canis, Trichuris vulpis, and Ancylostoma caninum in dogs under field conditions in Korea. This clinical study was conducted with client-owned dogs under field conditions from April 2023 to May 2024. The drug was administered on Day 0, and fecal samples were collected on Days - 7, 0, 7, and 14. Samples were analyzed using fecal flotation for qualitative assessment and the modified McMaster method for quantitative determination of egg counts. A total of 25 dogs from 25 different households were enrolled. The geometric mean reduction rates for all target nematode species and total infections were 100%. No adverse events or significant changes in body weight, physical examination findings, or hematology and serum chemistry parameters were observed. The results of this study support the effectiveness and safety of the drug against gastrointestinal nematodes in dogs under field conditions in Korea. These results indicate that this combination product may serve as a valuable tool in veterinary parasite control, ultimately contributing to improved canine health.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41264096/