Peer-reviewed veterinary case report
Local imipenem activity against Pseudomonas aeruginosa decreases in vivo in the presence of siliconized latex.
- Journal:
- European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
- Year:
- 2011
- Authors:
- Pichardo, C et al.
- Affiliation:
- Hospital Universitario Virgen del Rocí · Spain
Abstract
Zinc eluted from siliconized latex (SL) increases resistance of Pseudomonas aeruginosa to imipenem in vitro. A foreign body peritonitis model was used to evaluate the activity of imipenem using SL or silicone (S) implants. No differences were observed in mortality, positive blood cultures and tissue bacterial counts between SL and S implants. Implant-associated counts, however, were significantly higher in the SL group. It is concluded that SL decreases the activity of imipenem against P. aeruginosa.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20936490/