Peer-reviewed veterinary case report
Cat with sudden hind leg paralysis treated by artery urokinase
By Koyama, Hidekazu et al.·Published in The Journal of veterinary medical science·2010·Department of Veterinary Science, Japan·View original on PubMed →
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Original publication title: Local intra-arterial administration of urokinase in the treatment of a feline distal aortic thromboembolism.
- Species:
- cat
Plain-English summary
A 5-year-old neutered male cat suddenly became paralyzed in both hind legs and was rushed to the vet. Initially, the vet tried standard treatments with blood thinners and a medication called urokinase, but there was no improvement after two days. On the third day, the vet used a catheter to deliver urokinase directly into the affected artery, which successfully broke up the blood clot. By day five, the cat regained movement in his hind legs and was able to go home on day nine without any complications.
People also search for: cat hind leg paralysis treatment · urokinase for cat blood clots · cat thromboembolism recovery
Abstract
A 5-year old neutered male cat was admitted to our hospital in the early morning with sudden onset of bilateral hindlimbs paralysis. Conservative anticoagulant therapy using heparin, warfarin, and dipyridamole, and thrombolytic therapy with urokinase administered by intravenous infusion were started. However, no improvement was noted even after 2 days of treatment, and the cat was started on local intra-arterial administration of urokinase via a catheter on disease day 3. Successful thrombolysis could be accomplished by this approach, and the motor function of both hindlimbs recovered on disease day 5. The cat could be discharged on disease day 9. Complications such as hemorrhage and hyperkalemia were not observed during the thrombolytic therapy. These results suggest that local intra-arterial administration of urokinase may be an effective approach for the treatment of FATE.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20379085/