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Peer-reviewed veterinary case report

Localised apolipoprotein A-I amyloidosis arising in a fibroadnexal hamartoma in a dog.

Journal:
Veterinary dermatology
Year:
2025
Authors:
Murakami, Tomoaki et al.
Affiliation:
Tokyo University of Agriculture and Technology · Japan
Species:
dog

Abstract

Canine apolipoprotein A-I (ApoA-I) amyloidosis has only been reported as an age-related pulmonary vascular condition. In this report, the authors identified cutaneous ApoA-I amyloidosis within a fibroadnexal hamartoma in a dog. Based on proteomic analysis using mass spectrometry, the mechanism of ApoA-I amyloidogenesis is discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/39648810/