Peer-reviewed veterinary case report
Dog with rare localized pleural mesothelioma tumor
By Inanaga, Minori et al.·Published in Journal of comparative pathology·2023·Faculty of Pharmaceutical Science, Japan·View original on PubMed →
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Original publication title: Localized pleural mesothelioma in a dog.
- Species:
- dog
Plain-English summary
A 9-year-old male dog was diagnosed with a rare localized tumor in the chest, known as mesothelioma, which is a type of cancer that affects the lining of the lungs. After surgery to remove the tumor, the dog showed no signs of recurrence or spreading of the cancer 11 months later. The tumor was identified through special tests that confirmed it was not a different type of cancer. This case is significant because it highlights the importance of specific tests in diagnosing this unusual condition in dogs.
People also search for: dog chest tumor treatment · localized mesothelioma in dogs · dog cancer survival rates · signs of dog lung cancer
Abstract
Malignant mesotheliomas with localized growth are extremely rare in dogs. A 9-year-old male dog presented with a localized tumour that originated from the parietal pleura and had polypoid growth in the thoracic cavity. Histological examination revealed that the tumour consisted of tubular formations with scattered cysts and minimal papillary growth pattern. Neoplastic cells were immunopositive for mesothelial markers (calretinin and Wilms' tumour gene 1) and negative for carcinoma markers (thyroid transcription factor 1 and tumour protein 63). The animal was alive with no recurrence or metastasis/dissemination 11 months after surgery. To the best of our knowledge, this is the first report of a localized mesothelioma in a dog without metastasis/dissemination and highlights the value of mesothelial markers for an accurate diagnosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37922825/