Peer-reviewed veterinary case report
Pulmonary histiocytic sarcoma tumors in Pembroke Welsh Corgis
By Kagawa, Yumiko et al.·Published in The Journal of veterinary medical science·2016·North Lab, Japan·View original on PubMed →
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Original publication title: Localized pulmonary histiocytic sarcomas in Pembroke Welsh Corgi.
- Species:
- dog
Plain-English summary
A Pembroke Welsh Corgi was diagnosed with lung tumors after showing signs of breathing problems. The tumors were identified as histiocytic sarcomas, a type of cancer that affects the immune system. Unfortunately, the average survival time for dogs with this condition was about 133 days, and while surgery and chemotherapy were considered, they did not significantly improve outcomes. It's important for pet owners to be aware of this type of cancer if their dog has lung masses.
People also search for: Pembroke Welsh Corgi lung tumors · dog breathing problems cancer · histiocytic sarcoma treatment in dogs
Abstract
Nineteen cases of histiocytic sarcomas in Pembroke Welsh Corgi were examined histopathologically. Focal or multiple masses were detected in the lung or in regional lymph nodes, or in both lung and nodes. All neoplastic lesions had common histological features characterized by the proliferation of pleomorphic histiocytic cells combined with various inflammatory cells. Most of the pleomorphic neoplastic cells were immunopositive for human leukocyte antigen (HLA)-DR and Iba-1. The median survival time for all dogs was 133 days. In the present study, several prognostic factors, such as gender, age, single or multiple lesions, lymph node involvement at the time of diagnosis, surgical resection status and additional chemotherapy, were examined, although none of these factors approached statistical significance. Histiocytic sarcoma must be considered in the differential diagnosis of dogs with pulmonary masses, especially in the canine breed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26155931/