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Peer-reviewed veterinary case report

Miniature Schnauzer with Brain Tumor Treated Long-Term with Lomustine

By Jung, Dong-In et al.·Published in The Journal of veterinary medical science·2006·Department of Veterinary Internal Medicine, South Korea·View original on PubMed

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Original publication title: Long-term chemotherapy with lomustine of intracranial meningioma occurring in a miniature schnauzer.

Plain-English summary

A 14-year-old male miniature schnauzer was brought in because he was circling to the right. After brain scans, the vet found a mass that was likely a meningioma, which is a type of tumor in the brain. The dog was treated with a combination of prednisolone and lomustine (CCNU), a chemotherapy drug, which helped control his symptoms. Remarkably, he lived for thirteen months after the diagnosis, showing that this treatment can be effective for dogs with this condition.

People also search for: dog circling behavior · miniature schnauzer brain tumor treatment · lomustine for dogs with meningioma

Abstract

A 14-year-old male miniature schnauzer was referred to us because it was circling to the right. A mass in the diencephalon was noted on brain magnetic resonance images. The dura was thickened with marked linear enhancement after contrast administration. Based on diagnostic image analysis, this lesion strongly suggested meningioma. The patient's symptoms were well controlled by a combination therapy of prednisolone and lomustine (CCNU), and survived for thirteen months after diagnosis. This case was diagnosed as a meningioma based on histopathological findings. This report describes the clinical findings, imaging characteristics, and pathologic features of a diencephalic and mesencephalic meningioma and long-term survival after lomustine and prednisolone therapy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16679732/