Peer-reviewed veterinary case report
Dog with nasal olfactory tumor controlled by surgery and radiation
By Gumpel, E et al.·Published in Australian veterinary journal·2017·Brisbane Veterinary Specialist Centre, Australia·View original on PubMed →
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Original publication title: Long-term control of olfactory neuroblastoma in a dog treated with surgery and radiation therapy.
- Species:
- dog
Plain-English summary
An 8-year-old dog was brought to the vet because it was acting reclusive and pacing unusually. Imaging tests revealed a mass in the nasal cavity, which was diagnosed as olfactory neuroblastoma, a rare type of cancer. The tumor was not completely removed during surgery, so the dog received radiation therapy afterward. Despite the advanced stage of the cancer, the dog lived for 20 months after treatment, showing that aggressive therapy can help even in serious cases.
People also search for: dog nasal cancer treatment · olfactory neuroblastoma in dogs · dog pacing behavior causes
Abstract
BACKGROUND: Olfactory neuroblastoma is a rare malignancy of the nasal cavity in dogs that is thought to arise from specialised sensory neuroendocrine olfactory cells derived from the neural crest. CASE REPORT: An 8-year-old dog was presented for reclusiveness and pacing. On CT and MRI, a contract-enhancing mass was disclosed within the rostral fossa, extending caudally from the cribriform plate into the left nasal sinus. Surgical excision was performed and the diagnosis was histological grade III (Hyams grading scheme) olfactory neuroblastoma. Based on human CT criteria this was high stage (modified Kadish stage C). Surgical excision was incomplete and was followed by curative-intent radiation therapy using a linear accelerator to a total dose of 48 Gy. CONCLUSION: The dog survived 20 months after diagnosis. Although olfactory neuroblastoma is a rare tumour in dogs, aggressive local therapy may allow for prolonged survival, even when the tumour is advanced.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28653386/