Peer-reviewed veterinary case report
Long-term firocoxib helps dogs with osteoarthritis pain
By Autefage, A et al.·Published in The Veterinary record·2011·Unité, France·View original on PubMed →
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Original publication title: Long-term efficacy and safety of firocoxib in the treatment of dogs with osteoarthritis.
- Species:
- dog
Plain-English summary
Thirty-nine dogs with osteoarthritis were given a daily oral dose of firocoxib, a medication for pain and inflammation, for a year. Most owners noticed improvements in their dogs' comfort and mobility, with 82% reporting better conditions just two weeks into treatment. By the end of the study, 96% of the dogs that completed the trial showed significant improvement. The medication was generally well-tolerated, with very few dogs experiencing gastrointestinal side effects.
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Abstract
Thirty-nine client-owned dogs with osteoarthritis were treated with 5 mg/kg firocoxib administered orally, once a day for 52 weeks. Veterinary examinations were performed on approximately days 0, 15, 90, 180, 270 and 360. Twenty-five dogs completed the study. The withdrawal rate associated with gastrointestinal side effects was low (5.1 per cent of dogs). Based on the owners' assessment, 82 per cent of the dogs had improved at day 15, 84 per cent of the 32 remaining dogs had improved at day 90, and 96 per cent of the 25 dogs that completed the trial had improved at day 360. During this trial, 12 (48 per cent) of the 25 remaining dogs showed an improvement in their lameness from day 90 to day 360 (P<0.05).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21642297/