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Peer-reviewed veterinary case report

Long-term results of coil treatment for patent ductus arteriosus

By Hildebrandt, N et al.·Published in Journal of veterinary internal medicine·2010·Small Animal Clinic, Germany·View original on PubMed

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Original publication title: Long-term follow-up after transvenous single coil embolization of patent ductus arteriosus in dogs.

Species:
dog
Stomach & digestionDogs

Plain-English summary

A group of 28 dogs with a heart condition called patent ductus arteriosus (PDA) underwent a procedure where a small coil was placed to close the abnormal blood vessel. After about 2 years, 100% of the dogs with small PDAs had complete closure, while 50% of those with moderately sized PDAs still had a small residual shunt. Most dogs showed improvement, with 96% having no heart murmur after the procedure. This treatment effectively reduced heart strain and improved overall heart function in these dogs.

People also search for: dog heart murmur treatment · patent ductus arteriosus in dogs · PDA embolization success rate

Abstract

BACKGROUND: Long-term follow-up studies after interventional therapy of patent ductus arteriosus (PDA) in dogs are rare. HYPOTHESIS: Transvenous PDA embolization with a single detachable coil is a highly effective method in patients with an angiographically determined PDA&#x2264;4.0&#x2003;mm. ANIMALS: Twenty-eight dogs with an angiographic PDA&#x2264;4.0&#x2003;mm were included. METHODS: Prospective follow-up study after PDA coil embolization. RESULTS: The median follow-up time was 792 days (range, 2-3, 248 days). The rate of complete closure demonstrated by Doppler color flow was 54% at day 3 after intervention and the final cumulative rate was 71%. The rate of complete closure was significantly different between small and moderately sized PDA over the study period (P<.0001) and finally was 100 and 50%, respectively. In 16 dogs with complete closure, no recanalization was found. Disappearance of the continuous heart murmur was found in 89% after 3 days, and this increased to a final cumulative rate of 96%. Indexed left ventricular internal diameter in diastole (LVDd-I) decreased significantly (P<.0001). In the group with moderately sized PDA, a significant difference (P=.0256) was seen in LVDd-I between patients with and without residual shunt after exclusion of patients with persistent severe mitral valve regurgitation. CONCLUSION AND CLINICAL IMPORTANCE: Long-term follow-up after single coil embolization showed complete closure in all small PDA but a residual shunt with mild hemodynamic consequences was present in half of the moderately sized PDA.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21039864/