Peer-reviewed veterinary case report
Long-term inhaled steroid treatment helps dogs with eosinophilic
By Canonne, A M et al.·Published in The Journal of small animal practice·2016·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Long-term follow-up in dogs with idiopathic eosinophilic bronchopneumopathy treated with inhaled steroid therapy.
- Species:
- dog
Plain-English summary
A group of dogs with a breathing condition called eosinophilic bronchopneumopathy were treated with an inhaled steroid called fluticasone for 6 months to 5 years. Most dogs showed improvement in their coughing at first, with two dogs completely free of symptoms and three others well-controlled. However, three dogs experienced a severe return of symptoms over time. Additionally, two dogs had some hormonal side effects after long-term use, but only one showed noticeable signs of these issues. Overall, while fluticasone can help many dogs, it may not work for everyone in the long run.
People also search for: dog cough treatment · inhaled steroids for dogs · eosinophilic bronchopneumopathy in dogs
Abstract
BACKGROUND: Treatment of canine idiopathic eosinophilic bronchopneumopathy mainly consists of long-term oral corticosteroid therapy. To avoid side effects, inhaled steroid therapy has been increasingly used but long-term clinical response and potential side effects are sparsely described. OBJECTIVES: Description of clinical response and side effects with long-term fluticasone in dogs with eosinophilic bronchopneumopathy. METHODS: Case series of dogs with eosinophilic bronchopneumopathy and treated with fluticasone monotherapy for at least 6 months. Clinical response and side effects assessed by physical examination, standardised questionnaire and ACTH (corticotropin) stimulation test. RESULTS: Eight dogs were treated for between 6 months and 5 years. Cough initially improved in all dogs; two dogs remained free of clinical signs, three were well controlled, but three showed severe relapse. Pituitary-adrenal axis inhibition occurred in two dogs treated with fluticasone monotherapy for more than 2 years; only one dog had clinical signs of iatrogenic hyperadrenocorticism. CLINICAL SIGNIFICANCE: Fluticasone monotherapy allows initial improvement or remission in the majority of dogs but long-term treatment fails to resolve the cough in some individuals. In addition, such therapy may induce pituitary-adrenal axis inhibition. Prospective larger and randomised studies including both fluticasone and orally-treated dogs are needed to define the optimal treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27466969/