Peer-reviewed veterinary case report
Horse peeing and drinking a lot - long-term treatment options
By Durie, Inge & van Galen, Gaby·Published in Journal of veterinary internal medicine·2020·Equine Referral Hospital·View original on PubMed →
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Original publication title: Long-term hormone replacement treatment in a horse with central diabetes insipidus.
- Species:
- horse
Plain-English summary
A 4-year-old gelding was brought in for severe urination and excessive thirst, which were signs of central diabetes insipidus. After trying various treatments, the vet found that daily subcutaneous injections of desmopressin acetate were effective. This treatment helped the horse reduce its water intake and urination, and it remained healthy without any side effects for over five years.
People also search for: horse excessive thirst treatment · horse diabetes insipidus symptoms · desmopressin for horses
Abstract
This case report describes the clinical presentation, and the diagnostic and therapeutic approaches of a 4-year-old gelding presented with severe polyuria and polydipsia. The horse was diagnosed with central diabetes insipidus. After diagnosis, different therapeutic regimens with intraocular desmopressin acetate (Minirin, Ferring GmbH, Kiel, Germany) (a synthetic arginine vasopressin analog) were tested, but without success. Only the subcutaneous injection of desmopressin acetate (Minirin, Ferring GmbH) led to an increase in urine specific gravity and a decrease in water intake and urine output. Daily subcutaneous treatment with desmopressin acetate (Minirin, Ferring GmbH) was initiated and maintained for at least 5 years. The horse did not develop adverse effects or re-occurrence of the initial complaints. This case report describes successful long-term treatment of central diabetes insipidus in a horse.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31960998/