Peer-reviewed veterinary case report
Miniature Pinscher puppy footpad swelling after vaccine
By Kim, Ha-Jung et al.·Published in The Journal of veterinary medical science·2011·BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Disease and Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Long-term management of vaccine-induced refractory ischemic dermatopathy in a Miniature Pinscher puppy.
- Species:
- dog
Plain-English summary
A 2-month-old Miniature Pinscher puppy developed swollen footpads and crusty sores on her ears just five days after receiving a vaccine. The symptoms indicated a rare skin condition called ischemic dermatopathy, which was not responding to standard treatments. After trying several medications without success, the veterinarian switched to a combination of chlorambucil and cyclosporine, which effectively suppressed the puppy's immune response. Fortunately, her condition improved over time, and she showed no signs of relapse or side effects during a follow-up four months later.
People also search for: puppy skin problems after vaccination · Miniature Pinscher footpad swelling treatment · immune suppression for dog skin issues
Abstract
A 2-month-old intact female Miniature Pinscher puppy presented with footpad swelling and crusted pustules of ear pinnae. The dog had been vaccinated with a polyvalent canine vaccine 5 days prior to the onset of clinical signs. With the history of recent vaccination, the clinical presentation and the histopathological observations were suggestive of ischemic dermatopathy. Treatment involved oral prednisolone, azathioprine, and other immune modulating drugs, which did not work. Chlorambucil plus cyclosporine therapy was initiated for vigorous immune suppression after rush therapy using intravenous immunoglobulin. Clinical signs again gradually improved with no relapse or side effects, even at a 4-month follow-up. The case report is suggested ischemic dermatopathy refractory to conventional therapy and suggests effective approaches to long-term management of the disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21566400/