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Peer-reviewed veterinary case report

Long-term results of mitral valve repair in dogs with heart disease

By Kurogochi, Kentaro et al.·Published in Journal of veterinary internal medicine·2025·JASMINE Veterinary Cardiovascular Medical Center, Japan·View original on PubMed

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Original publication title: Long-Term Outcomes of Mitral Valve Repair With Artificial Chordae and Annuloplasty for Myxomatous Mitral Valve Disease in Dogs.

Species:
dog

Plain-English summary

A group of 1,019 dogs with myxomatous mitral valve disease (MMVD), which can lead to heart failure, underwent surgery to repair their mitral valve. The study found that during the first few months after surgery, some dogs experienced complications, but fewer had issues later on. Factors like older age, larger body weight, and specific breeds like Cavalier King Charles Spaniels were linked to a higher risk of problems after surgery. Overall, while some dogs faced challenges early on, many did well in the long term after the procedure.

People also search for: dog heart surgery recovery · Cavalier King Charles Spaniel heart problems · mitral valve disease treatment in dogs

Abstract

BACKGROUND: Myxomatous mitral valve disease (MMVD) in dogs commonly progresses to congestive heart failure, which carries a poor prognosis. Mitral valve repair (MVR) is a recognized treatment for advanced-stage MMVD. HYPOTHESIS/OBJECTIVES: Identify the risk factors and prognosis in dogs undergoing MVR. ANIMALS: We enrolled 1019 dogs with MMVD (ACVIM stages B2, C, and D) that underwent MVR between January 2017 and December 2020. METHODS: Medical records from a single institution were retrospectively reviewed. Early and late postoperative periods were defined as <&#x2009;100&#x2009;days and 100-1400&#x2009;days after surgery, respectively. The outcome was time to a composite of all-cause mortality, onset of postoperative congestive heart failure, or undergoing a second MVR (surgical revision). RESULTS: In the early postoperative period, 61 dogs experienced the composite outcome; in the late period, 211 dogs did. No dogs underwent a second MVR. The incidence rate was 19.6 and 7.1 events per 1000 dog-months in the early and late periods, respectively. Compared with stage B2 dogs, stage D dogs had 2.2 times the daily hazard of experiencing an early postoperative event. In the late period, increasing age (per year; hazard ratio [HR], 1.3), higher body weight (per kilogram; HR, 1.1), Cavalier King Charles Spaniels compared with Chihuahuas (HR, 2.2), and preoperative tricuspid valve regurgitant velocity >&#x2009;3.7&#x2009;m/s (HR, 2.5) were associated with the events. CONCLUSIONS AND CLINICAL IMPORTANCE: A higher incidence of the event was observed in the early postoperative period rather than later, with the outcome varying according to MMVD condition and patient-specific factors.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40525587/