Peer-reviewed veterinary case report
Long-term results of transvaginal mesh in younger women
By Li S et al.·2025·Department of Obstetrics and Gynecology, China·View original on Europe PMC →
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Original publication title: Long-Term Outcomes of Transvaginal Mesh in Younger Women: A Retrospective Study.
Plain-English summary
This study looked at the long-term results of a surgical procedure called transvaginal mesh (TVM) used to treat pelvic organ prolapse (POP) in younger women, specifically those aged 60 and under. Researchers followed 140 women who had the procedure between 2013 and 2023, and they found that 95.7% reported feeling cured after an average of about 52 months. The women also experienced significant improvements in their quality of life, and only a small number had issues like mesh exposure or pain during sex. Overall, the findings suggest that TVM is effective and has a low risk of complications for younger women with severe POP, without greatly affecting their sexual function.
Abstract
<h4>Introduction and hypothesis</h4>Despite FDA bans due to safety concerns, transvaginal mesh (TVM) offers lower recurrence rates for pelvic organ prolapse (POP) compared to native tissue repair. Current Chinese guidelines recommend TVM for recurrent or severe POP (POP-Q stage III-IV) in patients over 60 years. However, evidence regarding its long-term outcomes in younger patients (median age ≤ 60 years) remains limited.<h4>Methods</h4>This retrospective study included women who underwent TVM from 2013 to 2023 at a tertiary medical center. Baseline characteristics and perioperative details were extracted from electronic medical records. Follow-up data were collected through telephone interviews and/or in-person examination and questionnaires. Primary outcome was subjective surgical success. Secondary outcomes were quality of life changes and surgery-related adverse events, including mesh exposure, sexual dysfunction, and urinary complications.<h4>Results</h4>Of 728 women who underwent TVM, 140 (median age 56) were analyzed. At the last follow-up with a median of 52 months (IQR 12, 74), all 140 patients (100%) completed telephone questionnaires, while 42 (30.0%) additionally underwent in-person examination. The subjective cure rate was 95.7% (95% CI, 92.3-99.1%). Quality of life significantly improved postoperatively (both PFIQ-7 and PFDI-20 scores, P < 0.001). Only 4.3% (95% CI, 0.9-7.7%) had mesh exposure. Sexual activity and function remained stable, with a low rate of dyspareunia (4.3%).<h4>Conclusions</h4>TVM demonstrate satisfactory clinical results and a low complication rate in women ≤ 60 with severe POP. It does not significantly impair sexual function in patients who remain sexually active postoperatively.
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Search related cases →Original publication on Europe PMC: https://europepmc.org/article/MED/41454927