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Peer-reviewed veterinary case report

Long-term collagen supplement helps dogs with joint disease

By Cabezas, Miguel Ángel et al.·Published in Open veterinary journal·2022·Department of Medicine and Surgery, Spain·View original on PubMed

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Original publication title: Long-term supplementation with an undenatured type-II collagen (UC-II) formulation in dogs with degenerative joint disease: Exploratory study.

Species:
dog

Plain-English summary

A group of 110 dogs with joint pain from degenerative joint disease (DJD) were given a supplement called FLEXADINAdvanced, which contains undenatured type-II collagen (UC-II), for six months. Owners and veterinarians noticed significant improvements in the dogs' pain levels, mobility, and overall condition during this time. While many dogs showed good compliance with the treatment at the three-month mark, fewer continued consistently at six months. Overall, the supplement appeared to be an effective option for supporting joint health in dogs with mild to moderate DJD.

People also search for: dog joint pain supplement · UC-II for dogs arthritis · FLEXADINAdvanced for dogs

Abstract

BACKGROUND: Undenatured type-II collagen (UC-II) has demonstrated its benefits in degenerative joint disease (DJD) management. AIM: Exploratory clinical study to investigate the beneficial effects of FLEXADINAdvanced in dogs. METHODS: Multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADINAdvanced during 6 months. Pain, general condition, appetite, mobility, and lameness were assessed monthly by veterinarians and owners for 6 months. Compliance was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance,< 0.05). RESULTS: Parameters assessed were significantly lower comparing inclusion with all subsequent months (< 0.0001). Compliance at 3 months showed a good score but was significantly lower (< 0.0001) at 6 months. CONCLUSION: FLEXADINAdvanced, containing UC-II, can be considered as a good complementary feed to provide joint support in dogs with mild to moderate DJD.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35342740/