Peer-reviewed veterinary case report
Puppy with loperamide poisoning treated with naloxone and charcoal
By Staley, E C & Staley, E E·Published in Veterinary and human toxicology·1994·Veterinary Medical Clinic·View original on PubMed →
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Original publication title: Loperamide intoxication in a seven-week-old pup.
- Species:
- dog
Plain-English summary
A 7-week-old Samoyed-cross puppy showed signs of central nervous system issues, like circling, vocalization, and unresponsive pupils, after receiving two doses of loperamide, a medication often used to treat diarrhea. The puppy was treated with activated charcoal to help absorb the drug and naloxone, which helped reverse the effects of the loperamide. After several doses of naloxone over 12 hours, the puppy improved and was sent home for observation about 20 hours after the initial visit.
People also search for: puppy loperamide overdose treatment · why is my puppy circling · Samoyed puppy unresponsive pupils
Abstract
A 7-w-old Samoyed-cross pup was presented with central nervous system signs approximately 18 h following administration of the second of 2 doses of loperamide. Circling, vocalization, head pressing and unreactive pupils were present. There was no history of trauma. Improvement was seen shortly following administration of activated charcoal and 0.2 ml naloxone. Naloxone treatment was repeated at 2-h intervals over 12-h. Approximately 20 h following the initial clinical evaluation, the puppy was released to the owner for home care and observation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7839573/