Peer-reviewed veterinary case report
MRI features of multifocal vertebral lesions in dogs
By Furtado, Ana Rita Ramalho et al.·Published in The Veterinary record·2021·Dick White Referrals, United Kingdom·View original on PubMed →
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Original publication title: Low-field magnetic resonance imaging characteristics of multifocal vertebral lesions in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with multiple vertebral lesions underwent MRI scans to determine whether their conditions were aggressive or benign. The results showed that dogs with aggressive lesions experienced spinal pain, had new bone growth, and showed signs of spinal cord compression. In contrast, non-aggressive lesions displayed different imaging characteristics and were less likely to cause pain or other serious issues. Identifying these differences can help veterinarians decide on the best treatment options for affected dogs.
People also search for: dog spinal pain MRI results · dog vertebral lesions treatment · signs of aggressive bone disease in dogs
Abstract
BACKGROUND: There is a lack of information regarding magnetic resonance imaging (MRI) features of polyostotic vertebral lesions in dogs. The aim of this retrospective study was to identify and differenciate low-field MRI features of aggressive versus benign multifocal vertebral diseases in dogs. METHODS: MRI examinations from 49 dogs with polyostotic vertebral lesions were reviewed. Images were evaluated for vertebral intensity changes, expansile lesions, new bone formation, cortical bone interruption, paravertebral musculature changes, lymphadenomegaly, spinal cord compression and spinal cord signal changes. RESULTS: Twenty-nine dogs with non-aggressive bone lesions and 20 dogs with aggressive vertebral lesions were included. Non-aggressive lesions had variable T2-weighted fast spin-echo (T2W) signal intensity and the majority displayed low signal intensity on short tau inversion recovery (STIR). Aggressive lesions predominantly had high T2W and STIR signal intensity, with variable signal intensity on T1-weighted spin-echo and contrast enhancement. Aggressive lesions were associated with spinal pain (p < 0.01), new bone formation (p = 0.02), spinal cord compression (p < 0.01) and lymphadenomegaly (p < 0.01). Cortical interruption (p < 0.01) and paravertebral musculature changes (p < 0.01) were the strongest indicative imaging features for aggressive lesions. CONCLUSION: Spinal pain, spinal cord compression, new bone formation, lymphadenomegaly and especially cortical interruption and paravertebral musculature signal intensity changes were the best discriminators for differentiating malignant from benign vertebral lesions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34505679/