Peer-reviewed veterinary case report
Lung ultrasound features during the evolution of BPD: a study from an animal model.
- Journal:
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Year:
- 2026
- Authors:
- Zong, Haifeng et al.
- Affiliation:
- Shenzhen Maternity and Child Healthcare Hospital · China
- Species:
- rodent
Abstract
OBJECTIVE: To explore lung ultrasound (LUS) in the evolution of bronchopulmonary dysplasia (BPD) and the diagnostic value of LUS in BPD. METHODS: Newborn rats were randomly assigned to the room air (RA) group or the oxygen (O) group. LUS were performed at 12 h and on the 3rd, 7th, and 10th days to explore the LUS in BPD rats. Hematoxylin-eosin staining and immunohistochemical were analyzed to evaluate pathological characteristics. RESULTS: LUS score (LUSs) in the Ogroup was significantly increased on the 7th and 10th days. In the early stage, LUS revealed multiple B-lines and air bronchograms. In the late stage, LUS revealed anechoic echoic areas on the pleural surface and scattered dot-like hyperechoic patterns in the lung field. The LUS findings were consistent with the pathological results. CONCLUSION: There was a strong positive correlation between LUS and pathological findings. LUS can be used to monitor the evolution of BPD.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41506781/