Peer-reviewed veterinary case report
Lymphocytic-plasmacytic enteritis in two horses.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1990
- Authors:
- MacAllister, C G et al.
- Affiliation:
- Department of Veterinary Medicine and Surgery
- Species:
- horse
Plain-English summary
Two adult horses were experiencing ongoing weight loss, and tests showed they had low levels of a protein called albumin and high levels of globulins, which are antibodies. One of the horses also had anemia, a condition where there aren’t enough red blood cells, and signs of a serious blood clotting issue, along with a delayed response to a liver function test. Further testing indicated that their small intestines were not absorbing nutrients properly. The findings pointed to a condition called lymphocytic-plasmacytic enteritis, which means there was an abnormal immune response affecting the intestines, leading to malabsorption and loss of protein. The outcome of the treatment for these conditions is not specified in the abstract.
Abstract
The primary hematologic abnormalities in 2 adult horses with chronic weight loss were hypoalbuminemia and hyperglobulinemia. One horse was anemic, had subclinical disseminated intravascular coagulation, and prolonged plasma sulfobromophthalein half-life. Small-intestinal dysfunction with malabsorption was indicated by abnormal D-xylose absorption test results. Clinicopathologic and pathologic findings were consistent with a diagnosis of malabsorption and protein-losing enteropathy, attributable to lymphocytic and plasmacytic infiltration of the intestine.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/2365625/