Peer-reviewed veterinary case report
Chronic diarrhea and intestinal inflammation in 4 goats
By Pitel, Mariya O et al.·Published in Journal of veterinary internal medicine·2021·Department of Medicine and Epidemiology, United States·View original on PubMed →
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Original publication title: Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats.
- Species:
- goat
Plain-English summary
Four adult goats were brought to the vet for ongoing diarrhea that didn't improve with treatment for intestinal parasites. They showed signs of poor health, including weight loss and abnormal blood test results. After ruling out common infections and using imaging tests, the vets diagnosed them with lymphoplasmacytic and eosinophilic enteritis (a type of intestinal inflammation) through a biopsy. The goats were treated with corticosteroids, which helped them gain weight and stop the diarrhea, although some had relapses and complete recovery was challenging.
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Abstract
Four, mature, client-owned goats were presented to referral hospitals for recurrent diarrhea despite treatment for intestinal parasitism. Common clinical findings included diarrhea, poor condition, neutrophilia, and hypoalbuminemia. Testing for common infectious causes of diarrhea in goats was negative. Ultrasonography and computed tomography in 2 cases was suggestive of enteritis, including thickened intestinal walls and fluid filled, dilated small intestines, respectively. Lymphoplasmacytic and eosinophilic enteritis (LEE) was ultimately diagnosed on intestinal biopsy histopathology based on the presence of small intestinal villous blunting and increased numbers of lymphocytes and eosinophils predominantly within the lamina propria. Numerous globule leukocytes were also noted on histopathology in 3 cases. All goats responded favorably to corticosteroid treatment with weight gain and resolution of diarrhea and clinicopathologic abnormalities. Relapses occurred, and complete cure was difficult to achieve. Reported in other species, this series describes the clinical presentation, diagnosis, and treatment of LEE in adult goats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33934407/