Macroscopic changes of the cats liver during diseases.

Abstract

The main and most accessible part of pathomorphological research is the macro-scopic method, which makes it possible to effectively diagnose various animal diseas-es. Changes in the liver, as an organ in-volved in the process of digestion and meta-bolic reactions, are important in examining the pathogenesis and diagnosis of diseases. A macroscopic study of the liver of 15 cats with various diseases was performed. Among the animals subjected to a pathoana-tomic autopsy there were 9 cats and 6 cats, from 2.5 months to 18 years old. The most common changes were liver dystrophy: pro-tein, fat, protein-fat, which were registered in many diseases. The main diseases diag-nosed at the autopsy were infectious cat peritonitis, dipylidiosis, liver lipidosis, dis- eases of the digestive canal and kidneys, and bone tumors of the lower jaw. Alterative hepatitis was observed in an animal with infectious cat peritonitis. This disease was also accompanied by fibrinous perihepatitis. Cysts in the liver were observed with a simi-lar lesion of the kidneys. The mechanisms of development of iden-tified dystrophies are infiltration of substanc-es entering the liver with blood, and decom-position – the breakdown of complex chemi-cal compounds. Fibrinous perihepatitis is associated with the activity of macrophages that cause high permeability of the wall of small blood vessels, which makes it possible for large fibrinogen molecules to pass through, followed by the formation and ac-cumulation of fibrin. Alterative hepatitis with numerous small foci of necrosis is obvi-ously also associated with the activity of these inflammatory cells. Liver cysts, com-bined with similar changes in the cortical layer of the kidneys, and in one case, the mucous membrane of the bladder, indicate the innate nature of this pathology