Peer-reviewed veterinary case report
Dog with sudden back leg weakness diagnosed with vertebral
By Pérez-Martínez, Claudia et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2016·Institute of Biomedicine (IBIOMED) (Pé, Spain·View original on PubMed →
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Original publication title: Magnetic resonance imaging and immunohistochemistry of primary vertebral hemangiosarcoma in a dog and implications for diagnosis and therapy.
- Species:
- dog
Plain-English summary
A dog with sudden weakness in its back legs was found to have a mass on its spine after an MRI scan. The mass was diagnosed as a type of cancer called hemangiosarcoma, which affects blood vessels. Researchers noted that certain markers could help identify this cancer and guide treatment options. While the study suggests potential new therapies, the outcome for the dog was not detailed in the abstract.
People also search for: dog back leg weakness · hemangiosarcoma treatment in dogs · dog spine tumor symptoms
Abstract
A vertebral mass in a dog with an acute onset paraparesis was identified by magnetic resonance imaging. A poorly differentiated hemangiosarcoma was diagnosed by histopathology and immunohistochemistry. Endothelial nitric oxide synthase could be a new differential marker for poorly differentiated hemangiosarcoma in dogs. Immunohistochemical detection of p53 phosphorylated at Serine, p53, CD117, and CD44 suggest targets for design of therapeutic strategies.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27928170/