Peer-reviewed veterinary case report
Magnetic resonance imaging and immunohistochemistry of primary vertebral hemangiosarcoma in a dog and implications for diagnosis and therapy.
- Journal:
- The Canadian veterinary journal = La revue veterinaire canadienne
- Year:
- 2016
- Authors:
- Pérez-Martínez, Claudia et al.
- Affiliation:
- Institute of Biomedicine (IBIOMED) (Pé · Spain
- Species:
- dog
Abstract
A vertebral mass in a dog with an acute onset paraparesis was identified by magnetic resonance imaging. A poorly differentiated hemangiosarcoma was diagnosed by histopathology and immunohistochemistry. Endothelial nitric oxide synthase could be a new differential marker for poorly differentiated hemangiosarcoma in dogs. Immunohistochemical detection of p53 phosphorylated at Serine, p53, CD117, and CD44 suggest targets for design of therapeutic strategies.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27928170/