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Peer-reviewed veterinary case report

Brain MRI findings in two Yorkshire terriers with necrotizing

By von Praun, Ferdinand et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2006·Department of Small Animal Medicine, Germany·View original on PubMed

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Original publication title: Magnetic resonance imaging and pathologic findings associated with necrotizing encephalitis in two Yorkshire terriers.

Species:
dog
Brain & nervesDogs

Plain-English summary

Two young adult Yorkshire terriers showed signs of neurological problems, such as difficulty with coordination and other brain-related issues. MRI scans revealed abnormal areas in their brains, particularly in the cerebral cortex, which appeared differently on various imaging tests. A diagnosis of necrotizing encephalitis, a serious brain condition, was confirmed through further examination of brain tissue. Unfortunately, the outcome for these dogs is not specified, but this condition often requires intensive treatment and can be serious.

People also search for: Yorkshire terrier neurological problems · necrotizing encephalitis in dogs · MRI brain scan for dogs

Abstract

Two young adult Yorkshire terriers had neurologic signs consistent with forebrain and brainstem involvement or forebrain involvement alone. On magnetic resonance imaging studies there were asymmetric bilateral lesions mainly in the cerebral cortex, and in the diencephalon. These areas were hyperintense on T2-weighted and FLAIR images, but hypointense or isointense on T1-weighted images. Lesions had a varying degree of contrast enhancement. Areas which were isointense on T1-weighted images had no contrast enhancement or only foci of contrast enhancement. Lesions with hypointensity in T1-weighted images had no enhancement or more frequently ring-like enhancement around the lesion. Necrotizing encephalitis was confirmed pathohistologically in both dogs. The degree of contrast enhancement appeared to be related to the degree of lymphohistiocytic inflammation on histologic examination.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16700176/