Peer-reviewed veterinary case report
MRI and surgery fix cleft palate in 4-week-old male puppy
By Tolwani, Ravi et al.·Published in Contemporary topics in laboratory animal science·2004·Department of Comparative Medicine, United States·View original on PubMed →
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Original publication title: Magnetic resonance imaging and surgical repair of cleft palate in a four-week-old canine (Canis familiaris): an animal model for cleft palate repair.
- Species:
- dog
Plain-English summary
A 4-week-old male puppy with a complete cleft palate was successfully treated with surgery to repair the defect. This condition can cause feeding difficulties and other health issues, so the surgical repair aimed to improve the puppy's quality of life. The procedure showed promise for advancing research into similar conditions in humans. After the surgery, the puppy was expected to have a better chance of normal development and health.
People also search for: puppy cleft palate treatment · cleft palate surgery in dogs · feeding problems in puppies
Abstract
Successful cleft palate repair (palatoplasty) was accomplished in a male canine pup from a kindred with autosomal recessive transmission for a complete cleft palate phenotype. This case represents the potential application of a new animal model for cleft palate repair. This reproducible congenital defect provides a clinically relevant model to improve research into the human anomaly, as compared with previous iatrogenic or teratogenically induced animal models. This case report presents the basis for new repair techniques and for studying the genetic basis of the cleft palate defect.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15636550/