Peer-reviewed veterinary case report
MRI shows pituitary lobe shift in dogs with Cushing's disease
By Taoda, Takahiro et al.·Published in The Journal of veterinary medical science·2011·Department of Small Animal Surgery 2, Japan·View original on PubMed →
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Original publication title: Magnetic resonance imaging assessment of pituitary posterior lobe displacement in dogs with pituitary-dependent hyperadrenocorticism.
- Species:
- dog
Plain-English summary
A group of 28 dogs with pituitary-dependent hyperadrenocorticism (PDH), a condition that can cause symptoms like increased thirst, urination, and appetite, underwent MRI scans to check for changes in their pituitary gland. The scans showed that in these dogs, the posterior lobe of the pituitary was pushed upward and had a different appearance compared to healthy dogs. This information can help veterinarians diagnose issues like pituitary tumors and decide on the best treatment options.
People also search for: dog pituitary gland problems · hyperadrenocorticism symptoms in dogs · MRI for dog pituitary tumor treatment
Abstract
The displacement and signal intensity (SI) of the pituitary posterior lobe were evaluated on T1 weighted magnetic resonance (MR) images in 28 dogs with pituitary dependent hyperadrenocorticism (PDH). Compared with normal dogs, the posterior lobe was displaced dorsally in the pituitary of the PDH dogs. Correlation between the pituitary height/brain area (P/B) ratio and the displacement of the posterior lobe in the PDH dogs suggests that dorsal displacement of the posterior lobe increases in accordance with enlargement of the pituitary. As to the SI of the posterior lobe, the PDH dogs showed significantly lower SI in comparison to the normal dogs. Taken together, these results suggest that assessment of the displacement and SI of the posterior lobe of the pituitary on T1-weighted MR images is useful for the diagnosis of pituitary adenoma. In pituitary microadenoma that presents no apparent tumorigenesis on MRI, evaluation of these values may be useful for diagnosis and selection of an appropriate therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21233596/