Peer-reviewed veterinary case report
MRI features and treatment outcomes of vertebral chondrosarcoma
By Roynard, P F P et al.·Published in The Journal of small animal practice·2016·Long Island Veterinary Specialists, United States·View original on PubMed →
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Original publication title: Magnetic resonance imaging, treatment and outcome of canine vertebral chondrosarcomas. Six cases.
- Species:
- dog
Plain-English summary
Six dogs with vertebral chondrosarcoma, a type of bone cancer affecting the spine, were treated and monitored. They showed symptoms related to back pain and mobility issues, and MRI scans revealed abnormal masses in their vertebrae. Three of the dogs underwent surgery to remove the tumors, while one received medical treatment. Although the dogs that had surgery improved quickly, two of them experienced regrowth of the tumors later on. This type of cancer tends to be aggressive, and the best outcomes depend on whether the tumors can be completely removed through surgery.
People also search for: dog back pain · vertebral chondrosarcoma treatment · dog spine tumor surgery · dog cancer prognosis
Abstract
OBJECTIVES: To report the clinical presentation, magnetic resonance imaging features, treatments and outcomes of canine vertebral chondrosarcoma. MATERIALS AND METHODS: Retrospective review of medical records of dogs with confirmed vertebral chondrosarcoma and magnetic resonance imaging of the lesions, from four different veterinary referral institutions. RESULTS: A total of six dogs were included in this report. In all cases, magnetic resonance imaging revealed a lobulated mass involving the dorsal vertebral compartment, markedly hyperintense with few foci of hypointensity on T2-weighted images, iso to hypointense on T1-weighted images with contrast enhancement after gadolinium administration. Intralesional surgical resection was performed in three dogs and medical management in one, two dogs were euthanased and all lesions were submitted for histopathology. Magnetic resonance imaging findings correlated with histological findings of a low tumour grade. Rapid clinical improvement was noted after surgery but two of three dogs had local regrowth. CLINICAL SIGNIFICANCE: Chondrosarcomas show local aggressiveness and resistance to conventional radiotherapy and chemotherapy, and so prognosis depends on feasibility of en bloc resection. Magnetic resonance imaging may be helpful in establishing a presumptive diagnosis and prognosis based on the feasibility of surgical resection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27627693/